March 20 - Sunrise Seminars SS1/1
Spreading Depolarization
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| 07:45 - 08:05 |
SS1.1 (3) Spreading depolarization in acute neuronal injury
Jens P Dreier Center for Stroke Research, Department of Experimental Neurology and Neurology, Charité University Medicine Berlin, Germany |
| 08:05 - 08:25 |
SS1.2 Arguments why spreading depolarization will lead us nowhere
Andreas Unterberg Department of Neurosurgery, University of Heidelberg, Germany |
| 08:25 - 08:45 |
SS1.3 (25) Spreading depolarizations: monitoring a neuronal pathophysiologic process in traumatic brain injury
Jed A Hartings Department of Neurosurgery, University of Cincinnati College of Medicine, Cincinatti, OH, USA |
| 08:45 - 08:55 | Discussion |
March 20 - Sunrise seminars SS1/2
Communication with the Comatose Brain
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| 07:45 - 08:05 |
SS2.1 (4) Imaging covert cognition and consciousness
Athena Demertzi Cyclotron Research Centre, University of Li?ge, Li?ge, Belgium |
| 08:05 - 08:25 |
SS2.2 A new fMRI approach for establishing conscious awareness and communication in behaviourally nonresponsive patients (Cancelled attendance)
Lorina Naci The Brain and Mind Institute, Western University,London, ON, Canada |
| 08:25 - 08:45 |
SS2.3 (140) Right median nerve electrical stimulation improves the outcome of traumatic coma patients
Guo-yi Gao Department of Neurosurgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People's Republic of China |
| 08:45 - 08:55 | Discussion |
March 20 - Sunrise seminars SS1/3
Host factors: Comorbidities,Genomics and Epigenetics
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| 07:45 - 08:05 |
SS3.1 (75) TBI in an ageing population with co-morbidities and their therapies
Fiona Lecky School of Health and Related Research, University of Sheffield, Sheffield, United Kingdom |
| 08:05 - 08:25 |
SS3.2 Genetic Factors and Outcome Post TBI
Ramon Diaz-Arrastia Center for Neuroscience and Regenerative Medicine, Uniformed Services University of Health Sciences, Rockville, MD, USA |
| 08:25 - 08:45 |
SS3.3 (156) Rehabilomics Research: Examining Approaches to Personalized Medicine in TBI
Amy K Wagner Department of Physical Medicine and Rehabilitation, University of Pittsburgh, Pittsburgh, PA, USA |
| 08:45 - 08:55 | Discussion |
March 20 - Morning Plenary
State-of-the-art Lectures
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| 09:15 - 09:45 |
PL1 State-of-the-art Lecture on Traumatic Brain Injury
John T Povlishock Department of Anatomy and Neurobiology, Virginia Commonwealth University Medical Center, Richmond, VA, USA |
| 09:45 - 10:15 |
PL2 State-of-the-art Lecture on Spinal Cord Injury
Michael G Fehlings, Institute, University Health Network; Krembil Neuroscience Centre, Spinal Program, Toronto Western Hospital, University Health Network; Department of Surgery, Division of Neurosurgery and Spinal Program, University of Toronto, Canada |
| 10:15 - 10:45 |
PL3 Lifetime Perspective on Head Injury
Thomas A Gennarelli Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, USA |
March 20 - Pro and con session and parallel plenary session
PC1 ICP Monitoring
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| 13:45 - 13:50 |
Moderators intro
David K Menon |
| 13:50 - 14:00 |
PC1.2 (122) A Swine Model of Intracellular Cerebral Edema
Guy Rosenthal Guy Rosenthal, Fernando Ramirez de Noreiga, Samuel Moscovici, Eyal Itshayek, Ramez Abu Shkara, Yakov Felig, Geoffrey T Manley Hadassah-Hebrew University Medical Centre, Jerusalem, Israel |
| 14:00 - 14:10 |
PC1.3 (202) Optimal cerebral perfusion pressure - towards individualised treatment in severe traumatic brain injury
Marek Czosnyka Marcel J Aries1,2, Angelos G Kolias1, Marek Czosnyka1, Karol P Budohoski1, Luzius A Steiner3, Andrea Lavinio1,4,6, Ken M Brady5, David K Menon4,6, John D Pickard1, Peter J Hutchinson1, Peter Smielewski1 1Division of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke's Hospital & University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK 2Department of Neurology, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands |
| 14:10 - 14:40 |
PRO-CON Debate
Randall M Chesnut Dept. of Neurological Surgery, Harborview Medical Center, University of Washington, Seattle, WA, USA |
| 14:40 - 15:10 |
PRO-CON Debate
Andrew IR Maas Department of Neurosurgery, University Hospital Antwerp, Edegem, Belgium |
| 15:10 - 15:40 | Discussion |
March 20 - Pro and con session and parallel plenary session
PC2 Preclinical Discovery
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| 13:45 - 13:50 |
Moderators intro
W Dalton Dietrich |
| 13:50 - 14:00 |
PC2.1 (66) Treatment with combined EPO and BDNF supports hippocampal neurogenesis and improves functional outcome following focal TBI
Nicole Bye Nicole Bye, Alison Conquest, Alex Gotama, Jeffrey V Rosenfeld, Maria Cristina Morganti- Kossmann National Trauma Research Institute, Alfred Hospital and Department of Surgery, Monash University, Victoria, Australia |
| 14:00 - 14:10 |
PC2.2 (114) Characterization of TBI Models and Evaluation of Efficacy of Nicotinamide, Erythropoietin, and Cyclosporin A using Serum Biomarkers: Results from Operation Brain Trauma Therapy
Stefania Mondello Stefania Mondello1, Deborah A Shear2, Helen M Bramlett3, C Edward Dixon4, Kara Schmid2, W Dalton Dietrich3, Kevin KW Wang5, Ronald L Hayes6, Frank C Tortella2, Patrick M Kochanek4 1Department of Neuroscience, University of Messina, Messina, Italy 2Department of Applied Neurobiology, Division of Psychiatry and Neuroscience, Walter Reed Army Institute of Research, Silver Spring, MD, USA |
| 14:10 - 14:20 |
PC2.3 (44) Extracellular Matrix Biomarkers for Acute Neurological Injury
Jonathan Lifshitz Jonathan Lifshitz, Caroline Addington, Christine Pauken, Daniel R Griffiths, Sarah Stabenfeldt Barrow Neurological Institute at Phoenix Children's Hospital, Phoenix, Arizona, USA Department of Child Health, University of Arizona, College of Medicine - Phoenix, Phoenix, Arizona, USA Phoenix Veterans Administration Health Care System, Phoenix, Arizona, USA School of Biological and Health Systems Engineering, Ira A. Fulton Schools of Engineering, Arizona State University, Tempe, Arizona, USA |
| 14:20 - 14:50 |
PRO-CON Debate
Edward C Dixon Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA |
| 14:50 - 15:20 |
PRO-CON Debate
Esther Shohami Department of Pharmacology, Hebrew University of Jerusalem, Jerusalem, Israel |
| 15:20 - 15:40 | Discussion |
March 20 - Pro and con session and parallel plenary session
PP1 Assessing and Predicting Outcome
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| 13:45 - 14:05 |
PP1.1 (174) Predicting Outcome after TBI: current status and future perspectives
Ewout Steyerberg Department of Public Health, Erasmus MC - University Medical Center Rotterdam, The Netherlands |
| 14:05 - 14:25 |
PP1.2 (227) Outcome prediction in persistent post traumatic coma
Louis Puybasset Department of Anesthesiology and Critical Care; Pitié-Salp?tri?re Hospital,Pierre-and-Marie-Curie University, Paris, France |
| 14:25 - 14:45 |
PP1.3 (158) Head-Injured Patients Who Talk and Deteriorate: Analysis of 192 Cases Registered in the Japan Neurotrauma Data Bank
Takeshi Maeda Department of Neurosurgery, Nihon University School of Medicine, Tokyo, Japan |
| 14:45 - 15:05 |
PP1.5 (229) Outcome assessment after acquired brain injury
Nicole von Steinbüchel Dept. of Medical Psychology and Medical Sociology Georg August University, Göttingen, Germany |
| 15:05 - 15:15 | Discussion |
| 15:15 - 15:25 |
PP1.4 (43) Injury Severity and Seizure Development after Traumatic Brain Injury
Helen M Bramlett Helen M Bramlett, Justin Sick, Joseph Wasserman, Amade Bregy, W Dalton Dietrich, Thomas Sick Departments of Neurological Surgery and Neurology, The Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, Miami, Florida, USA Bruce W. Carter Department of Veterans Affairs Medical Center, Miami, Florida, USA |
| 15:25 - 15:35 |
PP1.6 (198) CT and MRI findings are not predictive of long-term outcome following mild traumatic brain injury
Paul McMahon Paul McMahon, Ava Puccio, Jamie Pardini, Allison Hricik, David O Okonkwo University of Pittsburgh, Pittsburgh, Pennsylvania, USA |
| 15:35 - 15:45 |
PP1.7 (223) Factors of influence on surgical decision making and outcome in patients with acute subdural hematoma: a retrospective study of 109 patients with evaluation of quality of live
TA van Essen TA van Essen, GC de Ruiter, WC Peul Department of Neurosurgery, Leiden University Medical Center, Leiden, The Netherlands Department of Neurosurgery, Medical Center Haaglanden, The Hague, The Netherlands |
| 15:45 - 15:55 | Discussion |
March 20 - Afternoon parallel plenary session
PP2 Diffuse Axonal Injury
International Society for Neurochemistry Symposium
on Diffuse Brain Injury
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| 16:10 - 16:30 |
PP2.1 (228) The Pathology of Diffuse Axonal Injury
Willie Stewart Department of Neuropathology, Institute of Neurological Sciences, Glasgow, United Kingdom |
| 16:30 - 16:50 |
PP2.2 (207) Tackling Concussion: Neuromechanics and Neuropathology
Douglas H Smith Center of Brain Injury and Repair, University of Pennsylvania, Philadelphia, PA, USA |
| 16:50 - 17:10 |
PP2.3 Delayed Onset of Axonal Demage Following Experimental TBI: Implications for chronic neurodegeneration in brain injury and disease
Ronald L Hayes Banyan Biomarkers Inc. / Banyan Laboratories, Alachua, FL, USA |
| 17:10 - 17:30 |
PP2.4 Therapeutic Targets
David O Okonkwo Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA |
| 17:30 - 17:40 | Discussion |
| 17:40 - 17:50 |
PP2.5 (214) Prognostic relevance of longitudinal brain atrophy estimation in posttraumatic diffuse axonal injury
Monti Emanuele Monti Emanuele1, Balbi Sergio1, Pedoia Valentina2, Binaghi Elisabetta2, Minotto Renzo3, Mauri Marco3, Sangiorgi Simone3, De Benedictis Alessandro3 1Dipartimento di Biotecnologie e Scienze della vita, Universita degli Studi dell'Insubria, Varese 2Dipartimento di Scienze teoriche ed applicate, sezione Informatica, Universita degli Studi dell'Insubria, Varese 3Ospedale di Circolo Fondazione Macchi, Varese |
| 17:50 - 18:00 |
PP2.6 (182) A Preliminary Study Serum ß-Actin as Potential Biomarker of Diffuse Axonal Injury in Severe Traumatic Brain Injury
Antonino Germano Antonino Germano, L Merlo, F Cimino1, A Speciale1, M Cristani1, D Fratantonio1, G Raffa, S Priola, RV Abritti, A Saija1, A David2 1Department Pharmaco-Biologico, Neurosurgical Clinic, University of Messina, Italy 2Intensive Care Unit, Neurosurgical Clinic, University of Messina, Italy |
| 18:00 - 18:10 |
PP2.7 (149) The cerebrovascular and axonal responses to repetitive mild traumatic brain injury in the juvenile rat
Takashi Miyauchi Takashi Miyauchi1,2, Enoch P Wei1, John T Povlishock1 1Department of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, Virginia, USA 2Yamaguchi Medical Center, Yamaguchi, Japan |
| 18:10 - 18:20 |
PP2.8 (69) Evaluating APP96- 110, a peptide derived from the Amyloid Precursor Protein, as a novel therapeutic agent against traumatic brain injury
Stephanie Plummer Stephanie Plummer1, Emma Thornton1, Frances Corrigan1, Robert Vink1, Roberto Cappai2, Corinna van den Heuvel1 1Adelaide Center for Neuroscience Research, The University of Adelaide, Australia 2Department of Pathology, The University of Melbourne, Australia |
| 18:20 - 18:30 | Discussion |
March 20 - Afternoon parallel plenary session
PP3 International Initiatives in Neurotrauma Research
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| 16:10 - 16:30 |
PP3.1 (204) NIH Participation in the International Traumatic Brain Injury Research (InTBIR) Initiative
Ramona Hicks National Institute of Health, National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA |
| 16:30 - 16:50 |
PP3.2 (175) The International Traumatic Brain Injury Research (InTBIR) Initiative
Philippe Cupers European Commission, Research and Innovation, Brussels, Belgium |
| 16:50 - 17:10 |
PP3.3 (222) Canadian Participation in the International Initiative for Traumatic Brain Injury Research (InTBIR)
Anthony G Phillips Institute of Neurosciences, Mental Health and Addiction, University of British Columbia, Vancouver, BC, Canada |
| 17:10 - 17:20 | Discussion |
| 17:20 - 17:30 |
PP3.4 (34) The Austrian Project. Improvement of prehospital and early hospital care of TBI patients: Goal and Methods of the study
Alexandra Brazinova Alexandra Brazinova1,2, Walter Mauritz2,3, Marek Majdan1,2 1Dept. of Public Health, Faculty of Health Care and Social Work, Trnava University, Slovakia 2International Neurotrauma Research Organisation, Vienna, Austria 3Trauma Center ?Lorenz Boehler?, Vienna, Austria |
| 17:30 - 17:40 |
PP3.5 (101) The effect of crossovers in the first randomised controlled trial of surgery for traumatic intracerebral haemorrhage [STITCH(trauma)]
Barbara A Gregson Barbara A Gregson, David A Mendelow, Elise N Rowan, Richard Francis, Patrick Mitchell Newcastle University, Newcastle, UK |
| 17:40 - 17:50 |
PP3.6 (99) Results from the first randomised controlled trial of surgery for traumatic intracerebral haemorrhage [STITCH(trauma)]
David A Mendelow David A Mendelow, Barbara A Gregson, Elise Rowan, Richard Francis, Patrick Mitchell Newcastle University, Newcastle, UK |
| 17:50 - 18:00 |
PP3.7 (37) The Austrian Project Improvement of prehospital and early hospital care of TBI patients Results of the study
Alexandra Brazinova Walter Mauritz1,2, Alexandra Brazinova1,3, Marek Majdan1,3 1International Neurotrauma Research Organisation, Vienna, Austria 2Trauma Center ?Lorenz Boehler?, Vienna, Austria 3Dept. of Public Health, Faculty of Health Care and Social Work, Trnava University, Slovakia |
| 18:00 - 18:10 |
PP3.8 (48) The effectiveness evaluation of helicopter ambulance transport among neurotrauma patients in Korea - Neurosurgical helicopter ambulance transport in small country
Jin Mo Cho Jin Mo Cho, Sook Jin Seo, Se-Hyuk Kim Ajou University, Suwon, Republic of Korea |
| 18:10 - 18:30 | Discussion |
March 20 - Afternoon parallel plenary session
PP4 Advanced Imaging
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| 16:10 - 16:30 |
PP4.1 (172) Quantitative assessment of cortical atrophy and axonal demyelination in severe traumatic brain injury using multimodal neuroimaging
Andrei Irimia Laboratory of Neuro Imaging, Department of Neurology, University of California, CA, USA |
| 16:30 - 16:50 |
PP4.2 (26) Functional MRI in TBI
Emmanuel A Stamatakis Division of Anaesthesia, School of Clinical Medicine, University of Cambridge, Cambridge, UK |
| 16:50 - 17:10 |
PP4.3 (234) Recovery of sensory-motor function of the lower limbs after complete paralysis: How, Why and What is to follow?
Reggie V Edgerton Department of Neurosurgery, University of California, Los Angeles, CA, USA |
| 17:10 - 17:20 | Discussion |
| 17:20 - 17:30 |
PP4.4 (120) Dynamic evolution of atrophy after moderate to severe traumatic brain injury
Virginia Newcombe Virginia Newcombe, Christian Ledig, Guilia Abate, Joanne Outtrim, Doris Chatfield, Thomas Geeraerts, Anne Manktelow, Peter J Hutchinson, Jonathan Coles, Guy Williams, Daniel Rueckert, David Menon Division of Anaesthesia, University of Cambridge Wolfson Brain Imaging Centre, University of Cambridge Department of Computing, Imperial College, London, UK |
| 17:30 - 17:40 |
PP4.5 (104) Quantitative Assessments of Traumatic Axonal Injury in the Living Human Brain: Combined Microdialysis and Advanced MRI Approaches
Sandra Magnoni Sandra Magnoni1, Christine L Mac Donald5, Thomas J Esparza5, Valeria Conte1, James Sorrell5, Giulio Bertani2,4, Riccardo Biffi3, Mario Macri4, Antonella Costa3, Brian Sammons5, Abraham Z Snyder5,6, Joshua Shimony6, Fabio Triulzi3, Nino Stocchetti1,4, David L Brody5 1Department of Anesthesia and Intensive Care, Fondazione IRCCS C Granda-Ospedale Maggiore Policlinico, Milan, Italy 2Department of Neurosurgery, Fondazione IRCCS C Granda-Ospedale Maggiore Policlinico, Milan, Italy 3Department of Neuroradiology, Fondazione IRCCS C Granda-Ospedale Maggiore Policlinico, Milan, Italy |
| 17:40 - 17:50 |
PP4.6 (135) Symptoms after mild traumatic brain injury correlate with cerebrovascular reactivity changes in BOLD MRI
Leodante da Costa Leodante da Costa, CHB van Niftrik, D Crane, J Fierstra, A Bethune Department of Surgery, Division of Neurosurgery, Sunnybrook Hospital, University of Toronto, Ontario, Canada |
| 17:50 - 18:00 |
PP4.7 (6) Very High Resolution Ultrasound Imaging to Assess the Injured Spinal Cord and Extent of Blood- Spinal Cord Barrier Disruption
Marc Soubeyrand Marc Soubeyrand, Anna Badner, Reaz Vawda, Young Sun Chung, Michael G Fehlings Division of Genetics and Development and Krembil Neuroscience Centre, Toronto Western Research Institute, Toronto, Ontario, Canada |
| 18:00 - 18:10 |
PP4.8 (231) Quantifying White Matter Structural Integrity with High Definition Fiber Tracking in Traumatic Brain Injury
David O Okonkwo David O Okonkwo, Walter Schneider, Nora Presson, Sue Beers, Lisa Marrow, Allison Borasso, Ava M Pucci Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA |
| 18:10 - 18:30 | Discussion |
March 21 - Sunrise seminars
SS2/4 BBB and Vascular Dysfunction
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| 07:45 - 08:05 |
SS4.1 (210) Vascular Compromise in Contusion Expansion
J Marc Simard University of Maryland School of Medicine, Baltimore, MD, USA |
| 08:05 - 08:25 |
SS4.2 (224) Blast-Induced Cerebral Vascular Dysfunction (Cancelled attendance)
Douglas DeWitt Charles R Allen Research Laboratories, Department of Anesthesiology, University of Texas Medical Branch, Galveston, TX, USA |
| 08:25 - 08:45 |
SS4.3 (136) Blood Brain Barrier Disruption Persists for Years After a Single Traumatic Brain Injury in Humans
Jennifer Hay Department of Neuropathology, Southern General Hospital, Glasgow, UK |
| 08:45 - 08:55 | Discussion |
March 21 - Sunrise seminars
SS2/5 Pediatric Neurotrauma
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| 07:45 - 08:05 |
SS5.1 Clinical Management
Anthony Figaji Institute for Child Health, Red Cross Children?s Hospital Rondebosch, University of Cape town, Cape Town, South Africa |
| 08:05 - 08:25 |
SS5.2 (10) Approaches and Decisions for Acute Pediatric TBI - An International Effort
Michael J Bell Safar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, PA, USA |
| 08:25 - 08:45 |
SS5.3 (22) Animal Models of Pediatric Traumatic Brain Injury
Susan Margulies Penn Engineering, University of Pennsylvania, Philadelphia, PA, USA |
| 08:45 - 08:55 | Discussion |
March 21 - Sunrise seminars
SS2/6 Axonal Pathfinding and regeneration
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| 07:45 - 08:05 |
SS6.1 (141) Regeneration and Relays in the Injured Spinal Cord
Armin Blesch German Center for Neurodegenerative Diseases, Bonn, Germany |
| 08:05 - 08:25 |
SS6.2 (14) Cytoskeletal Mechanisms of Axonal Growth and Regeneration
Frank Bradke German Center for Neurodegenerative Diseases, Bonn, Germany |
| 08:25 - 08:45 |
SS6.3 (188) Modeling spinal cord injury in the primate
Jacqueline C Bresnahan Brain and Spinal Cord Injury Center, Department of Neurological Surgery, University of California, San Francisco, CA, USA |
| 08:45 - 08:55 | Discussion |
March 21 - Morning plenary
Mild Traumatic Brain Injury
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| 09:15 - 09:45 |
PL4 (78) Biomarkers of Mild TBI
Bo-Michael Bellander Department of Clinical Neuroscience, Section for Neurosurgery, Karolinska University Hospital, Stockholm, Sweden |
| 09:45 - 10:15 |
PL5 (9) Treatment of Sports Related Concussion: Summary of the Current Recommendations of Three Prominent Sports Medicine Organizations
Donald W Marion The Defense and Veterans Brain Injury Center, Walter Reed Army Medical Center, Washington DC, WA, USA |
| 10:15 - 10:45 |
PL6 (23) Repetitive Mild Traumatic Brain Injuries
Mayumi Prins Ronald Reagan UCLA Medical Center, Department of Neurosurgery, David Geffen School of Medicine, Los Angeles, CA, USA |
March 21 - 3 minute Flash presentations
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| 10:45 - 10:48 |
F01 Amelioration of traumatic brain injury-induced increased cerebrovascular permeability by endothelial progenitor cells in mice
Nino Muradashvili Nino Muradashvili, Reeta Tyagi, Timothy E O?Toole, Suresh C Tyagi, David Lominadze University of Louisville, Louisville, KY, USA |
| 10:48 - 10:51 |
F02 A novel mouse model of penetrating TBI
Stefan Plantman Stefan Plantman, Marten Risling, Johan Davidsson Departement of Neuroscience Karolinska Institutet Stockholm, Sweden |
| 10:51 - 10:54 |
F03 Treatment with etifoxine improves functional recovery following traumatic brain injury in rats
Emmanuelle Simon O'Brien Emmanuelle Simon O'Brien, Marc Verleye Biocodex, Gentilly, France |
| 10:54 - 10:57 |
F04 Seizure susceptibility after traumatic injury to the pediatric mouse brain
Bridgette D Semple Bridgette D Semple1, Kayleen Gimlin1, Terence OBrien2, Linda Noble-Haeusslein1 1Department of Neurological Surgery, and Department of Physical Therapy and Rehabilitation, University of California San Francisco, San Francisco, CA, USA 2Dept. of Medicine (Royal Melbourne Hospital), Melbourne Brain Centre, University of Melbourne, Parkville, VIC, Australia |
| 10:57 - 11:00 |
F05 Characterisation of a Novel Model of Chronic Traumatic Encephalopathy
Kelly McAteer Kelly McAteer, Frances Corrigan, Emma Thornton, Corinna van den Heuvel, Robert Vink Discipline of Anatomy and Pathology, School of Medical Sciences, University of Adelaide, Adelaide, Australia |
| 11:00 - 11:03 |
F06 Measurement of biomarkers of brain damage in TBI patients recruited in the EPO-TBI randomised clinical trial
Hellewell SC Hellewell SC1,2, Conquest AL1,2, Bye N1,2, Morganti-Kossmann MC3,4,5 1National Trauma Research Institute, Alfred Hospital, Melbourne, Victoria, Australia 2Department of Surgery, Monash University, Melbourne, Victoria, Australia 3Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia 4Australian New Zealand Intensive Care Research Centre, Melbourne, Victoria, Australia 5Barrow Neurological Institute, Department of Child Health, University of Arizona, Phoenix, AZ, USA |
| 11:03 - 11:06 |
F07 Defining platelet function in polytrauma patients with traumatic brain injury upon admission to the emergency department
Gretchen M Brophy Gretchen M Brophy1, Bassem M Mohammed1, Nathan J White2, Erika J Martin1, Jason Newton1, Daniel Contaifer1, Jingmei Song1, Penny S Reynolds1, Kevin R Ward3, Donald F Brophy1 1Virginia Commonwealth University, Richmond, Virginia, USA 2Puget Sound Blood Center, Seattle, Washington, USA 3University of Michigan, Ann Arbor, Michigan, USA |
| 11:06 - 11:09 |
F08 PTSD and mild traumatic brain injury: changes in the serotonergic, noradrenergic and galanin systems
Lizan Kawa Lizan Kawa1, T Hökfelt1, D Agoston1,2, U Arborelius1, M Risling1 1Karolinska Institutet, Neuroscience, Stockholm, Sweden 2Uniformed Services University of the Health Sciences, Anatomy, Physiology and Genetics, Bethesda, Maryland, USA |
| 11:09 - 11:12 |
F09 Should patients with GCS score 13 be classified as moderate traumatic brain injury?
Cathrine Elisabeth Einarsen Cathrine Elisabeth Einarsen1,2, Rune Hatlestad Karlsen1, Stine Borgen Lund3, Kent Goran Moen1,3, Anne Vik1,3, Toril Skandsen1,2 1Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway 2Department of Physical Medicine and Rehabilitation, St. Olavs Hospital, Trondheim University Hospital, Norway 3Department of Neurosurgery, St. Olavs Hospital, Trondheim University Hospital, Norway |
| 11:12 - 11:15 |
F10 Different implications of mild traumatic brain injury - our experience
Mladen Karan Mladen Karan1, Kosta Petrović2, Vojislava Bugarski3, Bojan Jelača1, Vladimir Papić1, Đula Đilvesi1, Željka Nikolašević4, Petar Vuleković1 1Clinic of Neurosurgery, Clinical Centre of Vojvodina, Novi Sad, Serbia 2Radiology Centre, Clinical Centre of Vojvodina, Novi Sad,Serbia 3Neurology Clinic, Clinical Centre of Vojvodina, Novi Sad,Serbia 4Faculty of Philosophy, University of Novi Sad, Novi Sad, Serbia |
| 11:15 - 11:18 |
F11 Is N-acetylaspartate a measure of mitochondrial dysfunction after traumatic brain injury?
William Brooks William Brooks, Janna Harris, Henry Yeh, In-Young Choi, Phil Lee, Russell Swerdlow University of Kansas Medical Center, Hoglund Brain Imaging Center, Kansas City, Kansas, USA |
| 11:18 - 11:21 |
F12 Can magnetic resonance spectroscopy simultaneously probe links between edema and energy disruption following traumatic brain injury?
William Brooks William Brooks, Janna Harris, Henry Yeh, Phil Lee, In-Young Choi, Russell Swerdlow University of Kansas Medical Center, Hoglund Brain Imaging Center and Departments of Neurology, Biostatistics, and Molecular and Integrative Physiology, Kansas City, USA |
| 11:21 - 11:24 |
F13 Lateral Ventricle Volume Asymmetry Predicts Midline Shift and 6-month Outcome in Severe Traumatic Brain Injury
Arnold Tóth Arnold Tóth1, Ilona Schmalfuss2, Shelley C Heaton3, Andrea Gabrielli4, H Julia Hannay5, Linda Papa6, Gretchen M Brophy7, Kevin KW Wang8, András Büki1, Attila Schwarcz1, Ronald L Hayes9, Claudia S Robertson10, Steven A Robicsek11 1Department of Neurosurgery, University of Pécs, Pécs, Hungary 2Department of Radiology, North Florida/ South Georgia Veterans Administration & University of Florida, Gainesville, FL, USA 3Department of Clinical & Health Psychology, University of Florida, Gainesville, FL, USA 4Department of Anesthesiology & Critical Care, University of Florida, Gainesville, FL, USA 5Department of Psychology, University of Houston, Houston, TX, USA 6Orlando Regional Medical Center, Orlando, FL, USA 7Department of Pharmacotherapy & Outcomes Science and Neurosurgery, Virginia Commonwealth University, Richmond, VA, USA 8Center for Neuroproteomics & Biomarkers Research Departments of Psychiatry & Neuroscience McKnight Brain Institute, University of Florida, Gainesville, FL, USA |
| 11:24 - 11:27 |
F14 Estimation of the prognostic value of brain stem segmentation by probabilistic tractography in severe traumatic brain injury and its verification by anatomical dissection
Dávid Kis Dávid Kis1, Adrienn Máté1, Zoltán Mencser1, Andrea Czigner2, Pál Barzó1 1Department of Neurosurgery, University of Szeged, Szeged, Hungary 2Institute of Anatomy, University of Szeged, Szeged, Hungary |
| 11:27 - 11:30 |
F15 Intraparenchymal electrode recordings of cortical spreading depolarisation and continuous seizure activity - neurovascular disruption and seizure oxygen thresholds
Toby Jeffcote Toby Jeffcote1, S Jewell1, C Pahl1, C Tolias1, D Walsh1, A Strong1, S Mulcahy2, M Boutelle2 1Kings College London 2Imperial College London |
| 11:30 - 11:33 |
F16 Effects of hydrostatic cerebrospinal fluid pressure in different body positions on cerebrospinal fluid movement
Klarica M Klarica M1, Vukić M2, Radoš M1, Jurjević I1, Erceg G1, Petošić A3, Orešković D4 1University of Zagreb, School of Medicine, Department of Pharmacology and Croatian Institute for Brain Research, Zagreb, Croatia 2Department of Neurosurgery, School of Medicine University of Zagreb, Zagreb,Croatia 3University of Zagreb, Faculty of Electrical Engineering and Computing, Dept. of Electroacoustics, Zagreb, Croatia 4Ruđer Bošković Institute, Department of Molecular Biology, Zagreb, Croatia |
| 11:33 - 11:36 |
F17 Matrix Metalloproteinase 9 Levels are Increased in Peri-Contusional Brain: A Paired Microdialysis Study
Mathew R Guilfoyle Mathew R Guilfoyle1, Adel Helmy1, Keri LH Carpenter1,2, David K Menon2,3, John D Pickard1,2, Peter J Hutchinson1,2 1Division of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK 2Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK 3Division of Anaesthesia, Department of Medicine, University of Cambridge, Cambridge, UK |
| 11:36 - 11:39 |
F18 National study of chronic subdural haematoma in the United Kingdom
Angelos G Kolias Angelos G Kolias1, Ian C Coulter2, Alexis J Joannides1, Barbara Gregson3, Paul M Brennan4, Peter J Hutchinson1 on behalf of the British Neurosurgical Trainee Research Collaborative (BNTRC) 1Division of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke's Hospital & University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK 2Division of Neurosurgery, James Cook University Hospital, Middlesbrough, UK 3Neurosurgical Trials Unit, University of Newcastle, Newcastle, UK 4Division of Neurosurgery, Western General Hospital & University of Edinburgh, Edinburgh, UK |
| 11:39 - 11:42 |
F19 Injured Spinal Cord Pressure Evaluation (ISCoPE) study - expansion duroplasty reduces spinal cord pressure in acute spinal cord injury
Phang IS Phang IS, Werndle MC, Varsos G, Smielewski P, Czosnyka M, Zoumprouli A, Papadopoulos MC Academic Neurosurgery Unit, St George's University of London, London Department of Neurosurgery, Cambridge University, Addenbrookes Hospital, Cambridge Department of Neuroanaesthesia, St George's NHS Trust, London |
| 11:42 - 11:45 |
F20 A time-course of histological and behavioral pathology associated with intracranial pressure elevation following moderate diffuse traumatic brain injury
Audrey Lafrenaye Audrey Lafrenaye, John T Povlishock Department of Anatomy and Neurobiology, Virginia Commonwealth University Medical Center, Richmond, VA, USA |
| 11:45 - 11:48 |
F21 Hypothermia in TBI for control of intracranial hypertension: Standalone therapeutic option or adjunct?
Deepak Gupta Deepak Gupta1, Ashish Bindra1, Pankaj Kumar Singh1, Peter Andrews2, SS Kale1, BS Sharma1 1Department of Neurosurgery and Neuroanesthesia, JPN Apex Trauma Centre, AIIMS, Delhi 2Department of Anesthesia, University of Edinburgh, UK |
| 11:48 - 11:51 |
F22 Pre- and Postoperative Cerebral Perfusion Assessments in Chronic Subdural Hematoma
Antonino Germano Antonino Germano, L Merlo, A Campenn1, G Trimarchi2, Baldari S1 1Department of Radiology - Nuclear Medicine, Neurosurgical Clinic, University of Messina, Italy 2Department of Economics, Neurosurgical Clinic, University of Messina, Italy |
| 11:51 - 11:54 |
F23 Remote-ischemic preconditioning as a prophylactic treatment for mild traumatic brain injury
Eugene Park Eugene Park1, Misbah Nadeem Lalani2, Andrew J Baker1,2,3 1Keenan Research Centre in the Li Ka Shing Knowledge Institute at St. Michael?s Hospital, Toronto, Canada 2Departments of Anesthesia & Surgery, University of Toronto, Toronto, Canada 3Department of Critical Care St. Michael?s Hospital, Toronto, Canada |
| 11:54 - 11:57 |
F24 The effect of mild traumatic brain injury (mTBI) on the structural plasticity of the axon initial segment (AIS)
Michal Vascak Michal Vascak, Anders H?nell, John E Greer, Kimberle M Jacobs, John T Povlishock Virginia Commonwealth University, School of Medicine |
| 11:57 - 12:00 |
F25 Molecular mapping of the brain of PACAP deficient and wild-type mice with imaging mass spectrometry
Rivnyák Ádám Rivnyák Á1, Maasz G2,3,4, Schmidt J2,3,4, Pirger Zs1,5, Mihalik A1, Kiss P1, Gaszner B1, Hashimoto H6, Tamás A1, Mark L2,3,4, Reglődi D1 1Department of Anatomy, PTE-MTA ?Lendulet? PACAP Research Team, Pécs, Hungary 2Department of Analytical Biochemistry Institute of Biochemistry and Medical Chemistry 3Imaging Center for Life and Material Sciences 4Janos Szentagothai Research Center, University of Pécs, Pécs, Hungary 5Chemical Ecology and Neurobiology, Department of Experimental Zoology, Balaton Limnological Institute, Centre for Ecological Research, Hungarian Academy of Sciences, Hungary 6Graduate School of Pharmacological Sciences, Osaka University, Osaka, Japan |
| 12:00 - 12:03 |
F26 Traumatic brain injury by controlled cortical impact in mice - time courses of neuroinflammation, corpus callosum demyelination, sensorimotor deficits, edema and lesion
Cho AH Cho AH, Taib T, Leconte C, Deou E, Palmier B, Plotkine M, Marchand-Leroux C, Besson VC Paris Descartes University, Sorbonne Paris Cité Faculté des Sciences Pharmaceutiques et Biologiques - Pharmacology of Cerebral Circulation, Paris, France |
March 21 - Roundtable discussions
Codman Neuro Seminar Surgical Approaches To TBI:
Bone Decompression And More
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|
| 10:45 - 10:50 |
Introduction
Prof. András Büki |
| 10:50 - 11:10 |
Who may benefit from Decompressive Carniectomy? Lessons to learn from recent and ongoing trials
Prof. Peter J Hutchinson Addenbrooke?s Hospital & University of Cambridge, Cambridge, United Kingdom |
| 11:10 - 11:30 |
Surgical approaches to TBI before and after decompression
Prof. Franco Servadei University Hospital of Parma, Parma, Italy |
| 11:30 - 11:45 |
Q&A Session & Closing Remarks
Prof. András Büki University of Pécs, Pécs, Hungary |
March 21 - Roundtable discussions
Round Table Discussion on Biomarkers in Neurotrauma
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|
| 13:30 - 13:55 |
Standardization of data collection - clinical experience: the Common Data Elements - approach
David O Okonkwo Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA |
| 13:55 - 14:20 |
Biomarkers of the acute phase in TBI of various severity
Viktoria Bogner Ludwig-Maximilians University, Munich, Germany |
| 14:20 - 14:45 |
Biomarkers of the chronic phase of TBI/markers of neurodegeneration
Ramon Diaz-Arrastia Uniformed Services University of the Health Sciences, Rockville, MD, USA |
| 14:45 - 15:10 |
Novel candidate biomarkers and novel avenues of assay development
Douglas H Smith University of Pennsylvania, Philadelphia, PA, USA |
March 21 - Roundtable discussions
CENTER-TBI: Investigator initiated research
questions and other global initiatives
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|
| 15:15 - 15:30 |
CENTER-TBI study
David K Menon Department of Anaesthesia, Addenbrooke?s Hospital, University of Cambridge, Cambridge, UK |
| 15:30 - 15:45 |
TRACK-TBI and CENTER-TBI: accelerating research by collaboration
Ramon Diaz-Arrastia1, David O Okonkwo2 1Center for Neuroscience and Regenerative Medicine, Uniformed Services University of Health Sciences, Rockville, MD, USA 2Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA |
| 15:45 - 15:55 |
CENTER-TBI in China
Guo-yi Gao Department of Neurosurgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People's Republic of China |
| 15:55 - 16:05 |
CENTER-TBI in India
Deepak Gupta Department of Neurosurgery and Neuroanesthesia, JPN Apex Trauma Centre, AIIMS, Delhi |
| 16:05 - 16:30 | Round table discussions |
March 22 - Sunrise seminar
SS3/7 Hypothermia for Spinal Cord Injury
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|
| 07:45 - 08:05 |
SS7.1 The use of therapeutic hypothermia targeting severe spinal cord injury
W Dalton Dietrich The Miami Project to Cure Paralysis, University of Miami, Miami, FL, USA |
| 08:05 - 08:25 |
SS7.2 Hypothermia for Spinal Cord Injury
Michael G Fehlings Institute, University Health Network; Krembil Neuroscience Centre, Spinal Program, Toronto Western Hospital, University Health Network; Department of Surgery, Division of Neurosurgery and Spinal Program, University of Toronto, Canada |
| 08:25 - 08:45 |
SS7.3 (5) Future directions of hypothermia therapy for traumatic brain injury from clinical studies in Japan
Eichi Suehiro Department of Neurosurgery, Yamaguchi University School of Medicine, Ube, Japan |
| 08:45 - 08:55 | Discussion |
March 22 - Sunrise seminars
SS3/8 Therapeutic Windows for Neuroprotection in Animals and Humans
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| 07:45 - 08:05 |
SS8.1 (142) Identifying the Therapeutic Window; the Issue of Timescales in Clinical versus Experimental Traumatic Brain Injury
Denes V Agoston Uniformed Services University of the Health Sciences, Bethesda, MD, USA |
| 08:05 - 08:25 |
SS8.2 (79) The Neuroprotective Therapeutic Windows for Inhibiting Post-TBI Secondary Injury are Similar in Animals and Humans
Edward D Hall Spinal Cord & Brain Injury Research Center,University of Kentucky, Chandler Medical Center, Lexington, KY, USA |
| 08:25 - 08:45 |
SS8.3 (20) Lessons in Critical Care Research from a Global Phase 3 Trial of Progesterone in Patients with Severe Traumatic Brain Injury (sTBI)
Neta R Nelson VP Project Management & Operations Besins Healthcare/ BHR Pharma, LLC affiliate, Herndon, VA, USA |
| 08:45 - 08:55 | Discussion |
March 22 - Sunrise seminars
SS3/9 Contemporary challenges in the care for severe TBI
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|
| 07:45 - 08:05 |
SS9.1 Antiplatelet therapy in TBI
Oliver W Sakowitz Department of Neurosurgery, University of Heidelberg, Heidelberg, Germany |
| 08:05 - 08:25 |
SS9.2 (159) Neurotraumathe role of the residents? The changing face of TBI care
Doortje Engel Department of Neurosurgery, Cantonal Hospital of St. Gallen, St. Gallen, Switzerland |
| 08:25 - 08:45 |
SS9.3 Hemostatic disorders after Traumatic Brain Injury
Marc Maegele Department of Trauma and Orthopedic Surgery, University of Witten/ Herdecke, Cologne-Merheim Medical Center, Cologne, Germany |
| 08:45 - 08:55 | Discussion |
March 22 - Morning plenary
Imaging in the assessment of TBI
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| 09:15 - 09:45 |
PL7 Novel imaging techniques for characterising TBI severity at admission
David O Okonkwo Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA |
| 09:45 - 10:15 |
PL8 Imaging approaches to mapping pathophysiology
David K Menon Division of Anaesthesia, University of Cambridge, Cambridge, UK |
| 10:15 - 10:45 |
PL9 Neuroanatomical substrates of TBI outcomes
Walter Schneider Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA |
March 22 - Pro and con session and parallel plenary session
PP5 Preclinical Neuroprotection
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| 13:45 - 14:05 |
PP5.1 (45) TBI-Preclinical Neuroprotection
Alan I Faden Department of Anesthesiology & Center for Shock, Trauma and Anesthesiology Research (STAR), National Study Center for Trauma and EMS, University of Maryland School of Medicine, Baltimore, MD, USA |
| 14:05 - 14:25 |
PP5.2 (176) Exercise Dependent Plasticity in the Injured Spinal Cord
John D Houle Department of Neurobiology and Anatomy, Spinal Cord Research Center, Drexel University College of Medicine, Philadelphia, PA, USA |
| 14:25 - 14:45 |
PP5.3 (221) Neuroprotection: Preclinical/Translational Discovery
Robert Vink Discipline of Anatomy and Pathology, Adelaide Centre for Neuroscience Research, School of Medical Sciences, University of Adelaide, Australia |
| 14:45 - 14:55 | Discussion |
| 14:55 - 15:05 |
PP5.4 (86) Pivotal role of vasopressin v1a receptors for brain edema formation, secondary brain damage and regulation of cerebral aquaporins following traumatic brain injury in mice
Katrin Rauen Katrin Rauen1, Raimund Trabold1, Viorela Pop2, Jerome Badaut2, Nikolaus Plesnila1,3 1Institute for Surgical Research & Department of Neurosurgery, University of Munich Medical Center, Munich, Germany 2Department of Pediatrics, Loma Linda University School of Medicine, Loma Linda, CA, USA 3Institute for Stroke and Dementia Research (ISD), University of Munich Medical Center, Munich, Germany |
| 15:05 - 15:15 |
PP5.5 (98) Riluzole provides neuroprotection and attenuates ischemia reperfusion injury following surgical decompression in experimental cervical spondylotic myelopathy
Spyridon Karadimas Spyridon Karadimas1,2, A Laliberte1,2, YS Chung2, WD Foltz3,4, MG Fehlings1,2,5 1Institute of Medical Sciences, University of Toronto, Ontario, Canada 2Division of Genetics & Development, Toronto Western Research Institute, and Spinal Program, Krembil Neuroscience Centre, University Health Network, Toronto, Ontario, Canada 3STTARR Innovation Centre, Department of Radiation Oncology, Princess Margaret Hospital, Toronto, Ontario, Canada 4Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada 5Department of Surgery, Division of Neurosurgery, University of Toronto, Toronto, Ontario, Canada |
| 15:15 - 15:25 |
PP5.6 (116) Bone marrow mesenchymal stromal cells drive protective M2 microglia polarization after brain trauma
Elisa R Zanier Elisa R Zanier, Francesca Pischiutta, Loredana Riganti, Federica Marchesi, Elena Turola, Stefano Fumagalli, Carlo Perego, Emanuela Parotto, Paola Vinci, Pietro Veglianese, Giovanna D?Amico, Claudia Verderio, Maria-Grazia De Simoni IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Department of Neuroscience; Milan, Italy |
| 15:25 - 15:35 |
PP5.7 (18) Blocking p75NTR signal reduces white matter damage and aids recovery after controlled cortical impact brain injury
Michael Beattie Michael Beattie, Sang Mi Lee, Amity Lin, Jeffrey Sacramento, Ernesto Salegio, Leda Mannent, Marie-Noelle Castel, Benoit Canolle, Jacqueline C Bresnahan 1Department of Neurological Surgery, Brain and Spinal Injury Center, University of California San Francisco, CA, USA 2Sanofi R&D, 1 avenue Pierre Brossolette, Chilly-Mazarin, France |
| 15:35 - 15:45 |
PP5.8 (85) Acute antagonism of the complement anaphylatoxin receptor C5aR improves the outcome from experimental spinal cord injury
Marc J Ruitenberg Marc J Ruitenberg1,2, Faith H Brennan1, Richard Gordon1, Linda V Blomster1, Hong Wa Lao1, Gary J Cowin3, Stephen M Taylor1, Trent M Woodruff1 1The School of Biomedical Sciences, The University of Queensland, Brisbane, Australia 2Queensland Brain Institute, The University of Queensland, Brisbane, Australia 3Centre for Advanced Imaging, The University of Queensland, Brisbane, Australia |
| 15:45 - 15:55 | Discussion |
March 22 - Pro and con session and parallel plenary session
PP6 Rehabilitation in Neurotrauma
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| 13:45 - 14:05 |
PP6.1 (76) Multi-target, dual-electrode deep brain stimulation of the thalamus and subthalamic area for treatment of Holmes? tremor after brain injury
Kazutaka Kobayashi Division of Neurosurgery, Department of Neurological Surgery, Nihon University School of Medicine, Tokyo, Japan; Johns Hopkins University School of Medicine, Baltimore, MD, USA |
| 14:05 - 14:25 |
PP6.2 Tau, P-tau alternations and linkage to tauopathy after TBI
Kevin KW Wang Center for Neuroproteomics & Biomarkers Research, Departments of Psychiatry and Neuroscience, University of Florida, Gainesville, FL, USA |
| 14:25 - 14:35 | Discussion |
| 14:35 - 14:45 |
PP6.3 (32) Manipulating initiation time and duration of environmental enrichment exposure after traumatic brain injury to more accurately mimic clinical rehabilitation
Anthony E Kline Anthony E Kline, Vincent V Mattiola, Jacob B Leary Physical Medicine & Rehabilitation, Safar Center for Resuscitation Research, Center for Neuroscience, Center for the Neural Basis of Cognition, Psychology, Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA |
| 14:45 - 14:55 |
PP6.4 (180) Long term outcome of severe TBI patients admitted to the largest neurotrauma center in Budapest
Gábor Nardai Gábor Nardai, Erzsébet Baracskai Péterfy Hospital and Trauma Center, Budapest, Hungary |
| 14:55 - 15:05 |
PP6.5 (31) Environmental enrichment restores attentional set-shifting and behavioral flexibility after controlled cortical impact injury in male rats
Corina O Bondi Corina O Bondi, Jeffrey P Cheng, Heather M Tennant, Naima Lajud, Christina M Monaco, Jacob Leary, Anthony E Kline Physical Medicine & Rehabilitation, Safar Center for Resuscitation Research, Center for Neuroscience, Center for the Neural Basis of Cognition, Psychology, Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA |
| 15:05 - 15:15 |
PP6.6 (194) Prognosis of severe traumatic brain injury in Hungary? Analysis of the first ten years of the ?Pécs Severe Head Injury Database?
Noémi Kovács Noémi Kovács1, Endre Czeiter1,2,3, Krisztina Amrein1,3, Erzsébet Ezer1, József Szabó4, Béla Demeter5, János Sándor6, András Büki1,2,3 1Department of Neurosurgery, University of Pécs, Pécs, Hungary 2MTA-PTE Clinical Neuroscience MR Research Group, Pécs, Hungary 3University of Pécs, János Szentágothai Research Centre, Pécs, Hungary 4Vas County Hospital, Szombathely, Hungary 5BAZ County Hospital, Miskolc, Hungary 6Department of Biostatistics and Epidemiology, University of Debrecen, Debrecen, Hungary |
| 15:15 - 15:25 |
PP6.7 Validation of a new coma scale: Emergency Coma Scale
Katsuji Shima Katsuji Shima1,2, Tomio Ohta2, Hiroshi Okudera2, Masaaki Iwase2, Yasuhiko Ajimi2 1Department of Neurosurgery, National Defense Medical College, Tokorozawa, Saitama, Japan 2Japan Society of Neurosurgical Emergency |
| 15:25 - 15:35 | Discussion |
March 22 - Pro and con session and parallel plenary session
PC3 Decompressive craniectomy
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|
| 13:45 - 13:50 |
Moderator's intro
Peter J Hutchinson |
| 13:50 - 14:00 |
PC3.1 (36) Decompressive craniectomy for severe traumatic brain injury: Ethical considerations
Stephen Honeybul Stephen Honeybul, Grant Gillet, Kwok Ho Sir Charles Gairdner Royal Perth Hospital, Nedlands, Australia |
| 14:00 - 14:10 |
PC3.2 (110) Morphological changes on cortical surface and their correlation of with neurological outcome in patients with bone defects after decompressive craniectomy
Arthur Maynart Pereira Oliveira Arthur Maynart Pereira Oliveira, Robson Luís Oliveira de Amorim, Wellingson Silva Paiva, Almir Ferreira de Andrade, Fernando Mendes Paschoal Junior, Edson Bor Seng Shu, Fernanda Coelho, Gabriel Scarabotolo Gattas, Renato Anghinah, Manoel Jacobsen Teixeira University of San Paulo, Department of Neurology, Discipline of Neurosurgery, Sao Paulo, Brazil |
| 14:10 - 14:20 |
PC3.3 (127) RESCUE-ASDH study - A randomised trial of primary decompressive craniectomy versus craniotomy for acute subdural haematomas
Angelos G Kolias Angelos G Kolias1, Antonio Belli2, Geoffrey T Manley3, Clare N Gallagher4, Andrew T King5, Ivan Timofeev1, A David Mendelow6, Gillian S McHugh7, John D Pickard1, Franco Servadei8, Peter J Kirkpatrick1, David K Menon9, Peter J Hutchinson1 on behalf of the RESCUE-ASDH Collaborative Group 1Division of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke's Hospital & University of Cambridge, Cambridge Biomedical Campus, Cambridge, UK 2NIHR Centre for Surgical Reconstruction and Microbiology, Queen Elizabeth Hospital & University of Birmingham, Birmingham, UK |
| 14:20 - 14:30 |
PC3.4 (148) 25 years experience of DC: the question has been reduced to only when and how instead of doing it or not
András Csókay A Csókay, L Lipóth, A Jósvai Military Hosp. Department of Neurosurgery, Budapest, Hungary |
| 14:30 - 15:00 |
PRO-CON Debate
Ji-yao Jiang Department of Neurosurgery, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, People?s Republic of China |
| 15:00 - 15:30 |
PRO-CON Debate
Jamie Cooper Intensive Care Research Centre, The Alfred Hospital, Melbourne, Australia |
| 15:30 - 15:50 | Discussion |
March 22 - Afternoon parallel plenary session
PP7 Non-Invasive and Multimodal Monitoring
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|
| 16:10 - 16:30 |
PP7.1 (27) Non-invasive ICP Monitoring
Marek Czosnyka Academic Neurosurgical Unit, University of Cambridge Clinical School, Cambridge, UK |
| 16:30 - 16:50 |
PP7.2 Microdialysis/Licox/ Autoregulation
Steven A Robicsek College of Medicine, University of Florida, Gainesville,FL, USA |
| 16:50 - 16:55 | Discussion |
| 16:55 - 17:05 |
PP7.3 (42) Assessment of the CerOx Cerebral Oxygenation Monitor in Severe Traumatic Brain Injury Patients
Guy Rosenthal Guy Rosenthal, Alex Furmanov, Eyal Itshayek, Yigal Shoshan, Vineeta Singh Hadassah-Hebrew University Medical Center University of California, San Francisco,USA |
| 17:05 - 17:15 |
PP7.4 (100) The clinical pitfalls and possibilities using S100B monitoring in neuro intensive care of patients suffering from traumatic brain injury
Eric Thelin Eric Thelin, Bo-Michael Bellander Karolinska Institutet, Department of Clinical Neuroscience, Section for Neurosurgery, Sweden |
| 17:15 - 17:20 | Discussion |
March 22 - Afternoon parallel plenary session
|
|
| 16:10 - 16:30 |
PP8.1 Identification of bloodbased metabolic markers of traumatic braininjury
Matej Oresic VTT Technical Research Centre of Finland, Espoo, Finland |
| 16:30 - 16:50 |
PP8.2 Current status of the clinical application of microdialysis
Peter J Hutchinson Department of Clinical Neurosciences, Addenbrooke?s Hospital & University of Cambridge, UK |
| 16:50 - 16:55 | Discussion |
| 16:55 - 17:05 |
PP8.3 (63) Energy Metabolism in Human Traumatic Brain Injury: 13C-Labelled Cerebral Microdialysis and High- Resolution Nuclear Magnetic Resonance Studies
Ibrahim Jalloh Ibrahim Jalloh, Carpenter KLH, Gallagher CN, Grice P, Howe DJ, Mason A, Timofeev I, Helmy A, Murphy MP, Kirkpatrick PJ, Menon DK, Sutherland GR, Carpenter TA, Pickard JD, Hutchinson PJ Division of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, UK |
| 17:05 - 17:15 |
PP8.4 (72) New microdialysis method for protein biomarker sampling in the neurointensive care setting
Lars Hillered Lars Hillered, Andreas Dahlin, Karlis Purins, Magnus Wetterhall, Jonas Bergquist, Klas Hjort, Per Enblad, Anders Lewén Div of Neurosurgery, Dept of Neuroscience and Div of Microsystems Technology, Dept of Engineering Sciences, Div of Analytical Chemistry, Dept of Chemistry, BMC, Uppsala University, Uppsala, Sweden |
| 17:15 - 17:20 | Discussion |
March 22 - Afternoon parallel plenary session
PP9 Inflammation and Oxidative Damage in CNS Injury
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|
| 16:10 - 16:30 |
PP9.1 (173) Inflammasomes in the Central Nervous System
Robert W Keane Department of Physiology and Biophysics, Miller School of Medicine; University of Miami, FL, USA |
| 16:30 - 16:50 |
PP9.2 (155) Immune Markers of Inflammation in TBI
Cristina Morganti-Kossmann Dept. of Epidemiology and Preventive Medicine, Monash University, Victria, Australia |
| 16:50 - 16:55 | Discussion |
| 16:55 - 17:05 |
PP9.3 (41) Protecting glia from oxidative stress during secondary degeneration following neurotrauma
Melinda Fitzgerald Melinda Fitzgerald, Ryan L O?Hare Doig, Sophie C Payne, Carole A Bartlett, Donna L Savigni Experimental and Regenerative Neurosciences, School of Animal Biology, The University of Western Australia, Stirling Hwy, Crawley WA, Australia |
| 17:05 - 17:15 |
PP9.4 (56) Recombinant Human Interleukin-1 Antagonist Modifies the Neuro-inflammatory Response to Severe Traumatic Brain Injury
Adel Helmy Adel Helmy, Mathew R Guilfoyle, Keri LH Carpenter, John D Pickard, David K Menon, Peter J Hutchinson University of Cambridge, Cambridge, UK |
| 17:15 - 17:20 | Discussion |